MY neurologist just prescribed Cymbalta for my chronic back and nerve pain. I've read that it's mostly an anti-depressant with some scant info on it's ability to supress neurological pain.
Has anyone here had any experience with this drug? It's generic name is duloxetine hcl. I'm reluctant to start it what with all the numerous bad side effects it could have.(I tend to be hypersensitive to most drugs of late. I've tried most of the latest drugs for pain, with bad luck in regards to the side effects etc... Am currently on opiate based pain meds(percoset, Morphine sulphate) which seem to work most of the time.) Both I and my neuro think it's a good idea to try other non-habit forming drugs so I won't develop over dependence on the addictive stuff.(been on the opiates for years now.)
My pain is from back injuries and some crush injuries. (radiculopathies and swelling around the L4-5 as well as 3 vertabrae in the C region and 2 in my neck. marked abcesses and anular fissures as well nerve pain in my legs and arms.)
I'd just had another mri done today to determine the best course of surgery, if any for my spine problems and will be seeing my neuro again in a couple of weeks on that.
Would be greatful if any here could relate their experience/knowledge of Cymbalta to me before I possibly make the mistake of dosing on yet another toxic drug.
very little imho, it does help your mindset to deal with the stress of pain though...joe
"none" <Vampyres@nettaxi.com> wrote in message news:fap741ddi1cthtpha6d6c3rnc6ieo9sjo8@4ax.com...> MY neurologist just prescribed Cymbalta for my chronic back and nerve> pain.> I've read that it's mostly an anti-depressant with some scant info on> it's ability to supress neurological pain.>
Has anyone here had any experience with this drug?> It's generic name is duloxetine hcl.> I'm reluctant to start it what with all the numerous bad side effects> it could have.(I tend to be hypersensitive to most drugs of late. I've> tried most of the latest drugs for pain, with bad luck in regards to> the side effects etc... Am currently on opiate based pain> meds(percoset, Morphine sulphate) which seem to work most of the> time.)> Both I and my neuro think it's a good idea to try other non-habit> forming drugs so I won't develop over dependence on the addictive> stuff.(been on the opiates for years now.)>
My pain is from back injuries and some crush injuries.> (radiculopathies and swelling around the L4-5 as well as 3 vertabrae> in the C region and 2 in my neck. marked abcesses and anular fissures> as well nerve pain in my legs and arms.)>
I'd just had another mri done today to determine the best course of> surgery, if any for my spine problems and will be seeing my neuro> again in a couple of weeks on that.>
Would be greatful if any here could relate their experience/knowledge> of Cymbalta to me before I possibly make the mistake of dosing on yet> another toxic drug.
I started Cymbalta 8 weeks ago along with my other med's. Maybe slight improvement with lower back pain due to old injury. Can't say my mood has improved but had absolutely no side effects to deal with. I'm taking 60mg per day and will check to see if an increase in dosage may return more positive results.
For what it's worth, Rich
On Fri, 25 Mar 2005 13:22:29 GMT, "xhead" <xhead@botkiller.com> wrote:
very little imho, it does help your mindset to deal with the stress of pain>though...joe>
"none" <Vampyres@nettaxi.com> wrote in message>news:fap741ddi1cthtpha6d6c3rnc6ieo9sjo8@4ax.com...>> MY neurologist just prescribed Cymbalta for my chronic back and nerve>> pain.>> I've read that it's mostly an anti-depressant with some scant info on>> it's ability to supress neurological pain.>>
Has anyone here had any experience with this drug?>> It's generic name is duloxetine hcl.>> I'm reluctant to start it what with all the numerous bad side effects>> it could have.(I tend to be hypersensitive to most drugs of late. I've>> tried most of the latest drugs for pain, with bad luck in regards to>> the side effects etc... Am currently on opiate based pain>> meds(percoset, Morphine sulphate) which seem to work most of the>> time.)>> Both I and my neuro think it's a good idea to try other non-habit>> forming drugs so I won't develop over dependence on the addictive>> stuff.(been on the opiates for years now.)>>
My pain is from back injuries and some crush injuries.>> (radiculopathies and swelling around the L4-5 as well as 3 vertabrae>> in the C region and 2 in my neck. marked abcesses and anular fissures>> as well nerve pain in my legs and arms.)>>
I'd just had another mri done today to determine the best course of>> surgery, if any for my spine problems and will be seeing my neuro>> again in a couple of weeks on that.>>
Would be greatful if any here could relate their experience/knowledge>> of Cymbalta to me before I possibly make the mistake of dosing on yet>> another toxic drug.>
On Mon, 28 Mar 2005 23:10:07 -0600, Rich <rnienowremove@hotmail.com> wrote something wonderfully witty:
I started Cymbalta 8 weeks ago along with my other med's.>Maybe slight improvement with lower back pain due to old injury.>Can't say my mood has improved but had absolutely no side effects to >deal with. I'm taking 60mg per day and will check to see if an>increase in dosage may return more positive results.>
For what it's worth,>Rich>
Everything I have read has said that 60mg is the maximum therapeutic dosage.
-- "patients who undertake opioid maintenance therapy should behave in a way that is beyond reproach or suspicion in all matters relating to their use of medications. Patients who are unwilling or unable to do so jeopardize not only their own health and safety, but the health and safety of other patients with chronic pain." -- Dr. Hurwitz
On Fri, 25 Mar 2005 04:36:17 -0600, none <Vampyres@nettaxi.com> wrote:
MY neurologist just prescribed Cymbalta for my chronic back and nerve>pain.>I've read that it's mostly an anti-depressant with some scant info on>it's ability to supress neurological pain.>
Has anyone here had any experience with this drug?>It's generic name is duloxetine hcl.>I'm reluctant to start it what with all the numerous bad side effects>it could have.(I tend to be hypersensitive to most drugs of late. I've>tried most of the latest drugs for pain, with bad luck in regards to>the side effects etc... Am currently on opiate based pain>meds(percoset, Morphine sulphate) which seem to work most of the>time.)>Both I and my neuro think it's a good idea to try other non-habit>forming drugs so I won't develop over dependence on the addictive>stuff.(been on the opiates for years now.)>
My pain is from back injuries and some crush injuries.>(radiculopathies and swelling around the L4-5 as well as 3 vertabrae>in the C region and 2 in my neck. marked abcesses and anular fissures>as well nerve pain in my legs and arms.)>
I'd just had another mri done today to determine the best course of>surgery, if any for my spine problems and will be seeing my neuro>again in a couple of weeks on that.>
Would be greatful if any here could relate their experience/knowledge>of Cymbalta to me before I possibly make the mistake of dosing on yet>another toxic drug.
It took a month for me to notice any difference. Then, almost overnight, two things happened:
1. Much lower base pain levels.
2. Much more sensitivity to my spinal cord stimulator.
On Tue, 29 Mar 2005 16:11:21 -0600, Jon Miller <jonmillere1@comcast.net> wrote something wonderfully witty:
On Fri, 25 Mar 2005 04:36:17 -0600, none <Vampyres@nettaxi.com> wrote:>
MY neurologist just prescribed Cymbalta for my chronic back and nerve>>pain.>>I've read that it's mostly an anti-depressant with some scant info on>>it's ability to supress neurological pain.>>
Has anyone here had any experience with this drug?>>It's generic name is duloxetine hcl.>>I'm reluctant to start it what with all the numerous bad side effects>>it could have.(I tend to be hypersensitive to most drugs of late. I've>>tried most of the latest drugs for pain, with bad luck in regards to>>the side effects etc... Am currently on opiate based pain>>meds(percoset, Morphine sulphate) which seem to work most of the>>time.)>>Both I and my neuro think it's a good idea to try other non-habit>>forming drugs so I won't develop over dependence on the addictive>>stuff.(been on the opiates for years now.)>>
My pain is from back injuries and some crush injuries.>>(radiculopathies and swelling around the L4-5 as well as 3 vertabrae>>in the C region and 2 in my neck. marked abcesses and anular fissures>>as well nerve pain in my legs and arms.)>>
I'd just had another mri done today to determine the best course of>>surgery, if any for my spine problems and will be seeing my neuro>>again in a couple of weeks on that.>>
Would be greatful if any here could relate their experience/knowledge>>of Cymbalta to me before I possibly make the mistake of dosing on yet>>another toxic drug.>
It took a month for me to notice any difference. Then, almost>overnight, two things happened:>
1. Much lower base pain levels.>
2. Much more sensitivity to my spinal cord stimulator.>
Jon Miller>
Did you also notice almost "Manic" type of episodes and have any problems sleeping? I have to say at this point I do have lower base pain levels, but I do also take it for depression as well which has all but abated at this time. -- "patients who undertake opioid maintenance therapy should behave in a way that is beyond reproach or suspicion in all matters relating to their use of medications. Patients who are unwilling or unable to do so jeopardize not only their own health and safety, but the health and safety of other patients with chronic pain." -- Dr. Hurwitz
I have read that also and have not done a lot of research. Have you found any explanation as to why 60mg is the max? I'm assuming Cymbalta is relatively new and could that be the reason?
thank's Rich
On Tue, 29 Mar 2005 00:46:20 -0500, ZombyWoof <Zomby-Woof@Zappa.net> wrote:
On Mon, 28 Mar 2005 23:10:07 -0600, Rich <rnienowremove@hotmail.com>>wrote something wonderfully witty:>
I started Cymbalta 8 weeks ago along with my other med's.>>Maybe slight improvement with lower back pain due to old injury.>>Can't say my mood has improved but had absolutely no side effects to >>deal with. I'm taking 60mg per day and will check to see if an>>increase in dosage may return more positive results.>>
For what it's worth,>>Rich>>
Everything I have read has said that 60mg is the maximum therapeutic>dosage.
On Wed, 30 Mar 2005 14:14:20 -0600, Rich <rnienowremove@hotmail.com> wrote:
I have read that also and have not done a lot of research.>Have you found any explanation as to why 60mg is the max?>I'm assuming Cymbalta is relatively new and could that be the reason?>
thank's>Rich>
I guess that is the amount that the found to be therapeutic in the trials with no observed improvements at increased dosage levels. Or even worse at increased dosage levels some level of damage may begin to happen to other bodily systems. The long & short of it is I just don't why, only what I've read. I've heard of others being given a 90mg dosage as well. I spent two weeks at 30mg and then moved to 60mg and stayed there. My Doc usually starts folks out a little lower then regular dosing to look for negative side-effects.
On Tue, 29 Mar 2005 00:46:20 -0500, ZombyWoof <Zomby-Woof@Zappa.net>>wrote:>
On Mon, 28 Mar 2005 23:10:07 -0600, Rich <rnienowremove@hotmail.com>>>wrote something wonderfully witty:>>
I started Cymbalta 8 weeks ago along with my other med's.>>>Maybe slight improvement with lower back pain due to old injury.>>>Can't say my mood has improved but had absolutely no side effects to >>>deal with. I'm taking 60mg per day and will check to see if an>>>increase in dosage may return more positive results.>>>
For what it's worth,>>>Rich>>>
Everything I have read has said that 60mg is the maximum therapeutic>>dosage.
On Wed, 30 Mar 2005 15:29:49 -0500, ZombyWoof <Nobody@nomail.com> wrote:
On Wed, 30 Mar 2005 14:14:20 -0600, Rich <rnienowremove@hotmail.com>>wrote:>
I have read that also and have not done a lot of research.>>Have you found any explanation as to why 60mg is the max?>>I'm assuming Cymbalta is relatively new and could that be the reason?>>
thank's>>Rich>>
I guess that is the amount that the found to be therapeutic in the>trials with no observed improvements at increased dosage levels. Or>even worse at increased dosage levels some level of damage may begin>to happen to other bodily systems. The long & short of it is I just>don't why, only what I've read. I've heard of others being given a>90mg dosage as well. I spent two weeks at 30mg and then moved to 60mg>and stayed there. My Doc usually starts folks out a little lower then>regular dosing to look for negative side-effects.>
On Tue, 29 Mar 2005 00:46:20 -0500, ZombyWoof <Zomby-Woof@Zappa.net>>>wrote:>>
On Mon, 28 Mar 2005 23:10:07 -0600, Rich <rnienowremove@hotmail.com>>>>wrote something wonderfully witty:>>>
I started Cymbalta 8 weeks ago along with my other med's.>>>>Maybe slight improvement with lower back pain due to old injury.>>>>Can't say my mood has improved but had absolutely no side effects to >>>>deal with. I'm taking 60mg per day and will check to see if an>>>>increase in dosage may return more positive results.>>>>
For what it's worth,>>>>Rich>>>>
Everything I have read has said that 60mg is the maximum therapeutic>>>dosage.
On Tue, 29 Mar 2005 21:54:31 -0500, ZombyWoof <Zomby-Woof@Zappa.net> wrote:
<snip for space>>>
Did you also notice almost "Manic" type of episodes and have any>problems sleeping? I have to say at this point I do have lower base>pain levels, but I do also take it for depression as well which has>all but abated at this time.
No. But I do have that type of response from too much opiates, especially near bedtime, so the Cymbalta makes sleep easier.
On Wed, 30 Mar 2005 14:14:20 -0600, Rich <rnienowremove@hotmail.com> wrote:
I have read that also and have not done a lot of research.>Have you found any explanation as to why 60mg is the max?
In trials, higher dosages just didn't give more relief. My psychiatrist claims otherwise, but I haven't been able to find any documentation. I wonder why he claims otherwise. He drives a Lexus, too. Coincidence?
I was started on Cymbaltic 60 mg a day. This made the second pain medication I take every day. My psych thought that it might help with the chronic pain.
I didn't expect anything but was surprised that it did work in a way. It didn't do anything for the chronic pain in my back and neck but it helped the pain in my legs from the nerves with sciatic. I have noticed it has been a long time since my right leg has hurt and burned. It did help that.
I have been taking it now for 6 months and have had no side effects.
On Thu, 31 Mar 2005 10:56:55 -0600, Jon Miller <jonmillere1@comcast.net> wrote something wonderfully witty:
On Wed, 30 Mar 2005 14:14:20 -0600, Rich <rnienowremove@hotmail.com>>wrote:>
I have read that also and have not done a lot of research.>>Have you found any explanation as to why 60mg is the max?>
In trials, higher dosages just didn't give more relief. My>psychiatrist claims otherwise, but I haven't been able to find any>documentation. I wonder why he claims otherwise. He drives a Lexus,>too. Coincidence? >
Jon "the cynical" Miller>
My psychiatrist was on the review board for the drug and involved in the trials. He is very heavily involved in all sorts of research and is also a Chemist on top of being an MD psychiatrist. It is opinion that Cymbalta is going to prove to be very effective in a number of off-label uses. -- "patients who undertake opioid maintenance therapy should behave in a way that is beyond reproach or suspicion in all matters relating to their use of medications. Patients who are unwilling or unable to do so jeopardize not only their own health and safety, but the health and safety of other patients with chronic pain." -- Dr. Hurwitz
On Thu, 31 Mar 2005 10:54:04 -0600, Jon Miller <jonmillere1@comcast.net> wrote something wonderfully witty:
On Tue, 29 Mar 2005 21:54:31 -0500, ZombyWoof <Zomby-Woof@Zappa.net>>wrote:>
<snip for space>>>>
Did you also notice almost "Manic" type of episodes and have any>>problems sleeping? I have to say at this point I do have lower base>>pain levels, but I do also take it for depression as well which has>>all but abated at this time.>
No. But I do have that type of response from too much opiates,>especially near bedtime, so the Cymbalta makes sleep easier.>
Jon Miller>
Well here is another nice little side-effect for me. I hate been having problems regulating my body temp for the past couple of years. Cold really affected me badly and I suffered from horrible night sweats. After being on the Cymbalta I am no where as sensitive to cold as I was, and the night sweats are greatly improved. The drug really has had some really interesting side benefits in my case. It also appears to make me "immune" to the effects of alcohol. -- "patients who undertake opioid maintenance therapy should behave in a way that is beyond reproach or suspicion in all matters relating to their use of medications. Patients who are unwilling or unable to do so jeopardize not only their own health and safety, but the health and safety of other patients with chronic pain." -- Dr. Hurwitz
On 31 Mar 2005 16:27:13 -0800, "mamabear" <disartain@gmail.com> wrote:
I was started on Cymbaltic 60 mg a day. This made the second pain>medication I take every day. My psych thought that it might help with>the chronic pain.>
I didn't expect anything but was surprised that it did work in a way.>It didn't do anything for the chronic pain in my back and neck but it>helped the pain in my legs from the nerves with sciatic. I have>noticed it has been a long time since my right leg has hurt and burned.> It did help that.>
I have been taking it now for 6 months and have had no side effects.>
Great drug for nerve related pain... I have DDD and am waiting for the new disks to be FDA approved. I also take codeine. But the cymbolta has made a huge reduction in my pain. Altho there are side effects (kinda sleepy sometimes) and you will yawn alot at first.... It's definitely worth trying it. Stick with it at least a 10 days tho. Jim in san diego
I give cymbalta a thumbs up for right now... only been on it 3 weeks..I have been taking it for chronic pain and my appetite has decreased (GREAT!!) of course it has been helping with the pain too..my only concern is that my stomach started swelling and I started having a burning censation around my heart...The doctor put me in the hospital for observation because I have already had 2 heart attacks and I am only 54 years old and a female.. The found that I had a gastric ulcer, errosion, and my esophogus needed stretching....don't know what brought it on but I wouldn't think it would have been the cymbalta.
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