Sunday, 4 June 2006
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| Antioxidants and Asthma Bob 17:52:18 |
| | Here's an interesting tidbit from May's issue of Thorax which suggests a dietary role of antioxidants in asthma.
http://thorax.bmjjournals.com/cgi/content/abstract/61/5/388
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| Science Creates The HypoAllergenic Cat Steven L. 06:01:22 |
| | The Sunday Times June 04, 2006
Clinical kitty: science comes up with the non-allergy cat Jonathan Leake and Jonathan Milne
It is not to be sneezed at. Breeders have solved a main drawback to owning a cat by producing a hypoallergenic kitten that saves its owner from sniffles, tears and asthma attacks.
An American company claims its scientists have bred the world’s first cats that cannot trigger human allergies and is now set to sell them in the UK for £7,500 each.
The cat is the latest designer pet to emerge from America and could provide relief for the 2.6m UK asthma sufferers whose attacks are triggered by their animals. Research published last month found that babies may be at 50% greater risk of developing eczema if their family has a cat.
Megan Young, chief executive of Allerca Lifestyle Pets, the company behind the allergy-free cat, said: “For the first time, people who have allergies will be able to keep a cat without suffering. This is a scientific breakthrough.”
Cat allergies are caused by a protein in the cat’s skin flakes and saliva deposited on the fur when the animal grooms itself by licking. It can trigger an allergic reaction in minutes if breathed by an asthma sufferer.
Scientists at Allerca, based in San Diego, analysed the genes of British and American shorthair cats to identify those with proteins that did not provoke a reaction in humans. By breeding the cats over several generations they produced more than 20 allergy-free offspring.
According to Allerca, preliminary tests on human volunteers have proved encouraging. The Scripps Research Institute, a California medical research group, is now carrying out controlled trials.
http://tinyurl.com/hlj2j
[ Well, it's not as exciting as re-creating dinosaurs in Jurassic Park, but it's a lot more useful. ]
-- Steven D. Litvintchouk Email: sdlitvin@earthlinkNOSPAM.net Remove the NOSPAM before replying to me.
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Friday, 2 June 2006
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| Blood in Urine--results Jason Johnson 23:45:15 |
| | Red Blood Cells were found in my urine and my doctor referred me to a urol. This is what happened:
A urologist examined me today in relation to the Red Blood cells that were found in my urine. These are the results:
1. The nurse told to provide a urine sample and I complied. The urologist later examined the urine under a microscope and found no evidence of blood.
I told him that I had some of the signs of kidney disease and felt that may have been the reason for the blood in the urine. He reviewed about a dozen blood and urine tests and also asked me about a dozen questions related to the major symptoms of kidney disease. It was his conclusion that I do not have kidney disease but that I may develop kidney problems within the next ten years: These were the three reasons that he mentioned: 1. Edema--he called it "postural hypotention" 2. blood in the urine 3. Salt Sentitive--Blood pressure problems/Edema related to normal amounts of salt.
He said that as long as my serum creatinine remained at 1.1 MG/DL or below that I did not have to be concerned about kidney disease. I told him that I was eating a low protein diet and a salt resticted diet. He told me that it was a great idea and to continue that diet.
He checked my prostate gland and said that it was slightly enlarged and there were no nodules (spelling??). He said that most men that were 55 years old had slighly enlarged prostate glands so it was nothing to be concerned about.
I have to provide two other urine samples on different dates--the second urine of the day. I asked him why he did not want the first urine of the day? He said that he was looking only for blood cells and that it was difficult to find blood cells in the first urine of the days due to the thousands of particles in the first urine of the day. I forgot to ask him about a dipstick test on that urine. He plans to look at the urine under a microscope.
He advised me NOT to make a diagnosis of my medical problems based on information that I learned from the internet or books. I did not mention to him that various people told me the same thing in this and other newsgroups.
I was hoping that he would arrange for me to get an abdominal ultrasound but he did not mention it--perhaps because he did not find any blood in the urine that he checked.
He did not ask my opinions about any tests or exams that I wanted to have--it was obvious that he wanted to make all decisions in relation to those things.
He seemed to be a typical "old school" doctor that does not want patients to make any decisions related to treatment options. If he had asked--I was going to request an abdominal ultrasound; urine cultured test; and new PSA test
Thanks again for those people that provided advice.
Jason
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Wednesday, 31 May 2006
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| Clean the Air - CBS News Reports on effective EcoQuest Air Purification System Allergy Relief 14:12:16 |
| | Clean the air Posted: 5/16/2006 5:28:59 PM
Article: http://www.whptv.com/WHPHealth/story.aspx?content_id=7B34A7F0-F79C-4D63-873C-C9DD1E76B52E
News Video Segment: http://www.whptv.com//mediacenter/default.aspx?videoId=94941
Add kids to that mixture and you have yourself a hotbed of germs, bacteria, viruses and allergies. The staff at a local pre-school and daycare says these annoyances have been significantly decreased thanks to a new air filter system.
Teacher Laurel Ramos: "Once that system was in place, I noticed it right away. I don't blow my nose nearly as much, I don't cough"
Laurel Ramos is a teacher at the Goddard School in Mechanicsburg -- where owners Nancy and Ken Goss installed a new air purifier. It's called the Fresh Air system by Eco-quest and it uses high intensity UVX
light with a specially developed rare metal hydrophilic coating -- and a bunch of other technologies that I don't understand.
But, what does make sense to me and the staff at Goddard is this daily illness log. Shannon Murphy, director of the school took a look at a 3 week period in March and counted 40 illnesses -- about 2 to 5 kids per day. That was BE - or before EcoQuest. After the system was installed, she counted only 12 to 14 illnesses in a 3 week period.
In fact, the Goss' installed the system because the owners of other schools say they saw the same success.
Nancy Goss: "During flu season, they quoted me maybe 25 - 30 kids out of a 3 month period would be sick say last year for example, and then this year they saw maybe 5 or 10"
And the effect isn't just felt by the kids.
Teacher Rose Gustkey: "Before the system was in place I used to come to work stuffy and throat would be sore, now things are so much better, I come to work and
breath and it's not until come outside I start sneezing"
Since the system parents and teachers talk about how fresh the air smells, but our cameras can't pick that up One tangible piece of evidence comes from the need for boxes of tissues, or lack there-of
Shannon Murphy: "Normally I'm buying cases, and this time I think I ordered one case"
Teacher Sherrie Swartz: "I've been constantly coming in with colds it has made a difference in myself and my children, they're not using as many tissues every day."
So is it the power of suggestion -- or do air filter systems really help. Judith Gostin, an Industrial Hygienist with the Pennsylvania Department of Health says yes -- as long as they are installed correctly, and maintained properly -- which includes periodic cleaning and changing.
"Filters are really quite vital for improving overall indoor air quality and certainly filtering out pollen mold spores, dust and dirt of all kinds"
As for germs, well, Gostin says it's really difficult to prevent kids from spreading germs, but the basic hygiene rules of washing hands frequently, disinfecting surfaces and no sharing utensils and pacifiers
will help cut down on germs.
And that has everyone at The Goddard school flipping with delight.
-------------------------------------------- About EcoQuest International
EcoQuest is dedicated to improving the spaces where people live by providing innovative products and services designed to enhance and improve the quality, safety, convenience, and beauty of living indoors.
For more information about EcoQuest International and the Fresh Air product, visit: http://www.tryfreshair.com
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| asthma and endotoxin and list of banned Ozone Machines Joe 12:52:29 |
| | Exposure to endotoxin, a bacterial substance found commonly in outdoor and indoor air, makes mite-allergic asthmatics more sensitive to house dust and may place them at increased risk of asthma attack
http://www.sciencedaily.com/releases/2003/12/031210073755.htm
list is here
http://www.arb.ca.gov/research/indoor/o3g-list.htm
and consumer reports
http://www.arb.ca.gov/research/indoor/cr-05-2005.pdf
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| particulate pollution is causing disabilitypayments McS 07:29:48 |
| | a.. Hundreds of community health studies have linked daily increases in particle pollution to reduced lung function, greater use of asthma medications, and increased rates of school absenteeism, emergency room visits, hospital admissions, and premature death.iv a.. In people with heart disease, very short-term exposures of one hour to elevated fine particle concentrations have been linked to irregular heart beats and heart attacks.v a.. Long-term epidemiological studies have repeatedly demonstrated that people living in areas with high fine particle concentrations have an increased risk of premature death compared to those in cleaner cities.vi The risk of dying early from cardio-respiratory diseases and lung cancer is higher in more polluted areas.vii Lives might be shortened by one to two years on average.viii a.. Fine particle pollution is especially harmful to people with lung diseases such as asthma and chronic obstructive pulmonary disease (COPD), which includes chronic bronchitis and emphysema, because particles can aggravate these diseases.ix Exposure to fine particle air pollution can trigger asthma flare-ups and cause wheezing, coughing, and respiratory irritation in individuals with sensitive airways.x People with heart disease such as coronary artery disease and congestive heart failure and people with diabetes are at risk of serious cardiac effects.xi
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Sunday, 28 May 2006
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| Nothing seems to work for my severe Asthma Miles 14:04:05 |
| | I have very severe Asthma. It effects me 24/7 and has been that way for about 20 years now. I've been to several Dr.'s and all pretty much take the same route. Load me up with pills, inhalers etc. Nothing has ever made much of a difference.
I have been on Advair 500mg but have stopped after the warnings came out. I believe Advair helped a slight amount. I started Spirava which maybe helping but have to use a bit longer to really tell.
I've tried Asmacort, Singular, Flovent, Serevent, and a long list of other drugs with virtually zero improvement.
For most of the 20 years my asthma has been uncontrolled. Albuterol helps but often only for a short period (30 minutes or less). Even strong doses of Medrol or Prednisone have little effect.
I have been on Xolair injections for 2 years now. It seems to have reduced the number of very severe days and ER visits but has not improved my day to day health.
Anyone else here with very severe asthma where most typical asthma drugs do very little? If so, what have you done to control your asthma? I've heard people mention Asmanex. I am not familiar with that. Is there much success with it where other meds have failed?
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| WebMD.com validates Ozone Purifiers are Safe! Guest 09:54:55 |
| | Excerpts from WebMD Article dated 5/11/06 Written by Daniel DeNoon and reviewed by Louise Chang, MD
Ozone Purifiers are NOT Ozone Generators!
Included in the study were several ionic air purifiers made by The Sharper Image, including the popular Ionic Breeze Quadra. These machines produce detectable levels of ozone. But they did not emit dangerous levels of ozone, except when a Quadra model intended for a large room was tested in a tiny bathroom.
Whatever ozone comes from ionic air purifiers pales in comparison to the amount produced by ozone-generating air purifiers. These machines make ozone for one reason: That's what they are designed to do.
By contrast, the Sharper Image Ionic Breeze Quadra model -- an ionic air purifier, not an ozone generator -- built ozone to a maximum level of 40 parts per billion (ppb) in a large office. The FDA considers medical devices safe if they emit less than 50 ppb of ozone. The World Health Organization considers eight-hour ozone levels of 60 ppb to be acceptable.
Mark Connelly, senior director of appliances and home improvement for Consumer Reports, oversees the magazine's air-cleaner tests. "You don't want to say that anything that generates ozone is bad," Connelly tells WebMD. "A printer produces ozone, but just because printers sit on people's desks doesn't mean they should be taken off the market...."
Whatever ozone comes from ionic air purifiers pales in comparison to the amount produced by ozone-generating air purifiers. These machines make ozone for one reason: That's what they are designed to do.
"Sharper Image products were included in the study and, in fact, met all safety standards for ultra-low trace ozone emissions when the appropriate-sized models were used in the manufacturer-recommended room sizes," Stephens tells WebMD. "Why they chose to place the unit in a room size for which it is clearly not intended nor used is inexplicable."
Nizkorodov says he thinks California will set a limit on how much ozone a device will be allowed to generate. He guesses the limit will be between 10 and 100 milligrams of ozone per hour -- and his bet is on the lower limit. His study found that the Sharper Image Ionic Breeze Quadra puts out 2.2 milligrams of ozone per hour -- far below the lowest limit California is likely to set.
Complete WebMD Article: http://www.webmd.com/content/article/122/114532.htm
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Saturday, 27 May 2006
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| Harvard Professor comments on Ozone Air Purifiers...calls them safe! Guest 08:46:38 |
| | Dr. Harriet Burge's response to the UC Irvine study:
Comments by Dr. Harriet Burge on the paper "Quantification of Ozone Levels in Indoor Environments Generated by Ionization and Ozonolysis Air-Purifiers" from the University of California, Irvine:
Academic scientists in their "protective" environments tend to assume that for-profit businesses are primarily interested in the bottom line, and only secondarily in effects on people. When we design studies on specific products, we tend to test the hypothesis that whatever health or exposure effect we suspect is, in fact, present. We should, however, be testing the null hypothesis: that the product is not producing the effect we suspect.
The recent article on ozone generation by air cleaners (Quantification of ozone levels in indoor environments generated by ionization and ozonolysis air-purifiers by Britigan et al) is a case in point. Although the paper is well-written and the study carefully done, it does appear to test the hypothesis that the "air cleaners" produce inappropriate concentrations of ozone. They should have tested the null hypothesis (that the cleaners do not produce ozone). Clearly, when used as directed, the SI cleaners did not produce inappropriate ozone concentrations in their studies. Their tables make clear that under conditions of use suggested by the manufacturer ozone concentrations remain low (less than 22ppb). The only elevated concentration they report was obtained by using a large room sized unit inappropriately in a very small bathroom with no ventilation. It is noteworthy that they did not use the SI units in Office B, possibly because they suspected that little ozone would be recovered.
The SI Quadra and other electrostatic air cleaners are not designed specifically to produce ozone as are the "ozonolysis" units. The studies in this paper actually document that the SI air cleaners do not lead to unacceptable ozone concentrations when used appropriately. Unfortunately, the overall impression given by this article is that the SI units are the same as the"ozonolysis" units. This conclusion is clearly supported by the plethora of comments on the internet.
I have personally evaluated the SI electrostatic precipitators and reviewed testing performed by the manufacturer. I have no hesitation about using them in my own home. Even in my smallest bedroom (7x10ft) ozone levels do not reach the odor threshold, which is well below any health related guideline.
Harriet A. Burge PhD Adjunct Senior Lecturer, Harvard School of Public Health Director of Research and Development, Environmental Microbiology Laboratory http://www.sharperimage.com/SharperImageIonicResponse.html#harriet
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| UC Irvine Peer Reviewed Article States Ozone Air Purifiers are Safe! Guest 08:45:33 |
| | Letter to The Sharper Image from Sergey A. Nizkorodov, the author of the UC Irvine study:
From: Sergey Nizkorodov Sent: Thursday, May 11, 2006 1:36 PM To: Michelle Arney Cc: Sergey Nizkorodov Subject: Re: Your ozone study
Dear Ms. Arney,
Thank you very much for your letter of May 10, 2006.
My understanding is that Rob Britt had not seen a copy of my article, "Quantification of ozone levels in indoor environments generated by ionization and ozonolysis air-purifiers", which was recently published in the peer-reviewed Journal of American Waste and Management Association, before he wrote the piece(s) about which you are complaining.
I am just as disappointed as you are about the inaccuracies in Mr. Britt's article. He informs me that he has now read my article and is in the process of revising his piece(s), as you apparently requested he do.
I hope this e-mail answers your question.
Sincerely yours, Sergey Nizkorodov Assistant Professor of Chemistry Department of Chemistry 1102 Natural Sciences II University of California at Irvine Irvine, CA 92697-2025
Sergey Nizkorodov Department of Chemistry 1102 Natural Sciences II University of California at Irvine Irvine, CA 92697-2025
Office: RH377 Labs: RH385, RH350, RH512
Web: http://aerosol.chem.uci.edu/
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| The Truth Behind Ozone Machines! Guest 08:30:43 |
| | I will like to address this OZONE topic.
For starters, Robert Britt article was incorrect. There has been a correction made to his article. http://msnbc.msn.com/id/12707280/
EPA uses data that is old that is unreliable. In fact, on the website they even reference a source that goes back to 1913! On top of that, the data that is used is based off of older data. The most recent year of "study" was over a decade ago. A lot has happened since then! http://www.epa.gov/iaq/pubs/ozonegen.html#bibliography
I am sure you may not know this, but Ozone is NOT bad. There is always ozone around us. Without it, we would all be dead.
Dr. James Marsden (Bio: http://tinyurl.com/mvzon) a Regents Distinguished Professor at Kansas State University is an expert in this field. He is even briefs congress on his research. (Marsen addresses congress: http://tinyurl.com/jcknc) Marsden is a member of the Food Safety Consortium (http://www.uark.edu/depts/fsc/). When he talks, people listen.
Dr. Marsden has addressed this topic in a piece called, "Ozone Used For Air Purification", you can read it by clicking here: https://www.secure-session.com/files/16/916650/606591502/A99A0781A3/i/OzoneUsedForAirPurification.pdf
Further, Dr. Marsden was interviewed on this topic. This is a very interesting interview as he addresses this topic head on.
Dr. Marsden answers the question, "Is Ozone Bad for you?" http://www.youtube.com/watch?v=33dU4zPzpFo
The Unknown Truth Regarding Ozone! http://www.youtube.com/watch?v=Ydb2_pyZeJk
Dr. Marsden on the safety of the Purifiers! http://www.youtube.com/watch?v=3noyHesbeTA
Kansas State University Studies Support Purifiers! (This contradicts what the outdated EPA has to say, "ozone has little potential to remove indoor air contaminants".) http://www.youtube.com/watch?v=nKZx_RWjlDI
CBS News Features Air Purification Technology http://www.youtube.com/watch?v=zHLkfdWH7Ec
Last but not least, Harvard Senior Lecturer, Dr. Harriet A. Burge, Ph.D. is also quoted as stating that she "no hesitation about using them in my own home". Read it for yourself: http://www.sharperimage.com/SharperImageIonicResponse.html#harriet
Doesn't stop there, UC Irvine was upset with Robert Britt. They are quoted as saying, "I am just as disappointed as you are about the inaccuracies in Mr. Britt's article." (Full statement here: http://www.sharperimage.com/SharperImageIonicResponse.html#letter)
If these types of purifiers are good enough for UC Irvine, a Harvard Ph.D and a Regents Distinguished Professor who is counsel to the Unites States congress, I guess they are safe for my home as well.
PS: Not to mention all of talk about "bad ozone" comes strictly from the EPA. This is NOT the first time the EPA has mislead us. Remember this? http://www.cbsnews.com/stories/2003/08/09/national/main567489.shtml
Judge Blasts EPA! http://www.cbsnews.com/stories/2006/02/02/health/main1276366.shtml
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Friday, 26 May 2006
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| Dust mask advice SteveJ 21:38:15 |
| | I recently started a new job within the company I've worked at for six years. The job was advertised as a floor cover and window dressing measurer\ estimator. Since starting this job my employers have decided that they need me to cut carpets on a daily basis. I pointed out the fact that I'm asthmatic and this would be a problem for me. They said they would take medical advice but in the meantime I would have to cut them. I cut carpets for two days solid and have now had to take time off because my breathing became laboured and painful. Anyway I've a feeling that when I return to work they will still want me to cut the carpets, So I will need a good quality dust mask suitable for asthmatics and that won't inhibit my breathing. The ones I've used around the house when painting or sanding are only suitable to wear for short periods in my experience. Any help appreciated Steve
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| Quackery Mgb 20:10:45 |
| | As a board certifed allergist, I am appalled at what the American Public falls for. Many would rather believe a 30 min infomercial by a discredited author out to sell a book with no information other than innuendo and the unsupported claims.
A great web site that deals with "questionable" medical claims is www.quackwatch.com
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| REPOST:Rate your Asthma-related quality of life Ph.D. M.M.Murawski 20:09:29 |
| | This is a repost - I'd like to add to the message below that if you find the site interesting, please share it with others, post it on web-pages, etc. We hope to gather a large number of reponses in order to better understand how those with asthma feel about treatment. Thank you.
For those who suffer from asthma-
We are performing a study, based out of the Purdue University School of Pharmacy, looking at what people with asthma might feel improvements in their health are worth, in terms of time or money. This research has been approved by Purdue University's Committee for Research on Human Subjects. In order to accomplish this we have created a website that we believe people with asthma or breathing issues might find of interest. If you visit our site you will have an opportunity to answer questions about how much you would value hypothetical asthma treatment interventions. While doing so, you will also complete a well-validated quality of life in asthma questionnaire, which will be scored automatically. You will be able to compare your score to several other population samples, which will give you an idea of how you are doing, in terms of your asthma-related quality of life. The whole process should take 10-15 minutes, depending on the speed of your connection and how you answer questions. We believe this will be of great interest to anyone with asthma. I invite you to visit our website to see for yourself all that we are trying to accomplish with our project. (http://surveys.pnhs.purdue.edu/index.php?sid=10&token=) If you have any questions or concerns please contact me at murawski@p.p.edu (Replace the p.p in the above address with pharmacy.purdue to reach me)
Respectfully-
-- Matthew M. Murawski,R.Ph.,Ph.D. Associate Professor of Pharmacy Administration Department of Pharmacy Practice Purdue University R.Heine Pharmacy Building Room 502 575 Stadium Mall Drive West Lafayette, IN 47907-2051
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Wednesday, 24 May 2006
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| Asthma patients Guest 16:06:00 |
| | Could treating acid reflux actually help control asthma? Doctors know that not every asthma patient gets acid reflux, so they don't expect it to help everyone. But they hope it will help some. It will answer the question of who you should treat if it works, and almost equally important, who you shouldn't treat or who you shouldn't falsely give this medicine to thinking it's going to affect their asthma. Getting the proper medications and educating patients about asthma can save lives. Every year, about five thousand people die from asthma. Experts say most of those deaths are preventable. Check out the video about this study: http://www.groundhog.tv/apps/editor/staticplayer.jsp?clip=1147464200420.wmv"><img src="
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Tuesday, 23 May 2006
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| asthma help anyone? D 12:19:09 |
| | i am studying biomedical sciences, and as part of my course i have to complete a dissertation on asthma.i chose asthma as my six year old son also suffers from this disease. i would greatly appreciate if anyone could help me with any useful information on this?thanks
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| inhaled corticosteroids ineffective in infants Alison Chaiken 02:04:57 |
| | http://content.nejm.org/cgi/content/short/354/19/1998
Sorry if someone else has already posted this; I've been on vacation and haven't yet had a chance to catch up with the group.
-- Alison Chaiken "From:" address above is valid. (650) 236-2231 [daytime]http://www.wsrcc.com/alison/ Waging a war is simple, but running a country is very difficult. -- Pham Van Dong, first prime minister of unified Vietnam, 1976
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Monday, 22 May 2006
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| Re: Alveoli Regrowth Ted Edwards 19:13:42 |
| | mitch wrote:> Does anyone here know whether a study, due to start in England, to> regrow Alveoli is related to the older FORTE study of vitamin A (ATRA,> All Trans Retinoid Acid).
I don't know but you can find quite a number of references by going to http://www.dogpile.com and search on "regrow Alveoli" without the quotes, of course. I shall certainly keep an eye on this as emphysema/copd is my nemesis.
Ted
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| Letter to a professor of pharmacy. Was Rate your Asthma-related quality of life Richard Friedel 17:44:53 |
| | Professor Murawski wrote
"We are performing a study, based out of the Purdue University School of Pharmacy, looking at what people with asthma might feel improvements in their health are worth, in terms of time or money. This research has been approved by Purdue University's Committee for Research on Human Subjects...... The whole process should take 10-15 minutes, depending on the speed of your connection and how you answer questions."
Dear Professor,
I think that there are questions of concern to asthmatics with a much higher priority than your questions - like modern drug-based asthma treatment being seriously flawed and at loggerheads with scientific facts.
You seem to be referring to approval by an ethics committee so that ethics are generally relevant here. I. e. is asthma drug treatment itself ethical?
That simple basic matters may be left unchecked for long periods of time is shown by the fact that people took two thousand years to realise that Aristotle was wrong when he said that men had more teeth than women.
As regards a similar situation with asthma and breathing the medical world assumes that any reduction in upper airway cross section actually hinders respiration as if one were dealing with some simple experiment in school physics and not a living organism. This doctrine is typified by the statement that the nose only serves to warm etc. the breathed in air and does not serve the purpose of producing suction during an inspiration.
You refer to answering questions only taking a short time and I think you might give this question some consideration. No longer time should be necessary.
If you breathe through a gap defined between some round rod about as thick as a finger and your lips you can hardly fail to note that the depth of an inhale increases (and does not decrease as might be expected) with a reduction in the size of the gap providing the vocal chords are left open and do not confound the effects.
During the maneuver while breathing through the gap the chords will in any case tend to remain open.
If now the rod is removed the vocal chords will automatically close somewhat to perform an inhale, but with a little sensitivity one may keep them open. The result is then that inspiration is inhibited because inspiratory resistance is minimized and, one might suppose, inspiratory muscles have no antagonist. This experiment is at least as foolproof as demonstrating the knee jerk reflex.
This phenomenon is of crucial importance for asthma, since bronchodilator drugs unload the inspiratory muscles and would, dependent on the asthmatic's attitude and tactics, weaken them. There is abundant circumstantial evidence to show that asthma has increased with modern drug treatment and it is obvious to think of such increase being due to the treatment.
Consequently a good tactic to reduce asthma incidence would for school textbooks to stress the respiration-enhancing effect of a reduction in flow cross section and that, contrary to what seems to be current medical doctrine, depth of respiration is correlated with airway cross sections and is not just under the control of the will alone. Regards, Richard Friedel.
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Thursday, 18 May 2006
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| Increasing lung capacity Guest 22:13:49 |
| | Just as the title says.Is there anyway to do this?
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| Chronic Asthma-->Acute Bronchitis Jed 04:04:09 |
| | I was diagnosed with chronic asthma a few years ago, but so mild that it's usually not noticeable and regular use of an inhaler wouldn't be appropriate. However, it's the likely cause of repeated bouts of acute bronchitis that follows any cold or hay fever attack. Sometimes, the early use of a Ventolin inhaler is enough to stem the progression. Other times, like right now, I have to go on a short course of Prednisone (everyone's favorite drug).
I put a call in to the doc to see about strategies to prevent these epidodes, which happen 1-2 times a year. In the meantime, I'm wondering if anyone else has coped with- and resolved- this problem. I've had instant relief with an Albuterol nebulizer treatment at the clinic, so I was thinking about asking the doc about that for home use.
Thanks!
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Monday, 15 May 2006
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| re: asthma, or adrenal failure due to asthma inhaler-Advair? Pinkrainbow 15:54:28 |
| | Newbie as of today!) pinkrainbow2004@yahoo.ca Hi all, to be succinct, i seem to be going into adrenal failure, very possibly as a misdiagnosis of asthma, and treated with steroids..details to follow..it's a tad long, so if not interested, hit next!..otherwise...thankyou for listening! history:
-Diagnosed with asthma ,2 yearsago, after frequent bouts of bronchitis, pneumonia, sob, but mostly wheezing, especially with environmental changes, exercise, heat waves, etc... and consequent antibiotics.... on ventolin short-acting inhaler, advair 500mg. twice a day.(and a ton of other stuff, for pain, thyroid, sleep, etc
-Diagnosed with Addison's disease 4 months ago-my adrenal glands are shut-down..not producing hormone cortisol, which is necessary to sustain life, mainly for stress(fight or flight), infections,etc. I requested referral to respirologist, who said i don't have asthma (based on the pulmonary function tests, as i did not react to the asthma-stimulating test(?name)..but, i have narrowing of the vessels, so cat scan was ordered to rule out emphysema, and/or COPD.
Question:the respirologist said the majority of patients referred by their gp DO NOT have asthma...then he said the reason i have almost no serum cortisol(the hormone the adrenal glands, above the kidneys)produce, was that advair has a steroid component, which tells my body, 'i don't need to produce cortisol anymore.'...and my adrenal's go into "shutdown" ..so he wants me off it..so he reduced the advair 500mg. to 100mg., starting immediately...I was scarred of going into addisonian crisis,(the idea is, if i am off Adair the steroid, my body will tell my adrenals to wake up and start working)....i think it is too fast, as when i tried the 100mg.this morning, it felt like nothing, and i am now wheezy, sob, esp. on exertion, chest tightness...so i phoned him and requested a 'wean', he agreed, (but within a month!.....250mg. for 2 weeks, then 100mg. for 2 weeks, then nothing!)
Question- how long do you think is reasonable to wean off advair 500mg., after being on it for several years...(to complicate things further, my gp still thinks i have asthma, just wasn't off the inhalers long enough when the pulmonary f. tests were done..i was off 24 hours.) Secondly-if he thinks i may have emphysema(God forbid!yikes!), wouldn't you still need inhalers?..the cat scan will take months to get in..and i haven't seen an endo yet..also my gp(main dr., is moving in august, and it is almost impossible to get a gp in Toronto these days!) Lastly, Addison's is treated with hydrocortisol(cortef), or prednisone(synthetic..very strong, and in my opinion dangerous)..i am on bioidentical hormonal therapy for menopause and hypothyroidism),... I thought cortef is a long-acting broncho-dilator AND anti-inflammatory..this was my understanding...i am told, don't worry, when you stop the inhalers, the cortef will start the adrenals up again, BUT, i am NOT responding to this drug..my serum cortisol is still very, very low...zero is addisonian crisis and possible death. So if your asthmatic, i assume people are on steroid's, do other people not run into my problem?
I am hoping, that someone here, may' have Addison's and asthma', and know about the effect of these inhalers on the endocrine system, particularly the adrenals. By the way, i also have M.E.(CFS,CFIDS), fibromyalgia, ...perhaps a healthy person wouldn't have developed these problems..?
So any suggestions, advice, tips, or any feedback at all, even if it telling me off for bringing a sort-of 'off-topic, atypical post to your group..would be appreciated...most of this stuff i have to figure out myself these past 4 months...knowledge is power, and if i hadn't seen that specialist, i may have been treated as an asthmatic in inhalers the rest of my life! or..perhaps someone else here, has heard of, or gone thru something similar. Thanks for listening pinkrainbow
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Tuesday, 9 May 2006
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| Rate your Asthma-related quality of life Ph.D. M.M.Murawski 19:22:48 |
| | For those who suffer from asthma-
We are performing a study, based out of the Purdue University School of Pharmacy, looking at what people with asthma might feel improvements in their health are worth, in terms of time or money. This research has been approved by Purdue University's Committee for Research on Human Subjects. In order to accomplish this we have created a website that we believe people with asthma or breathing issues might find of interest. If you visit our site you will have an opportunity to answer questions about how much you would value hypothetical asthma treatment interventions. While doing so, you will also complete a well-validated quality of life in asthma questionnaire, which will be scored automatically. You will be able to compare your score to several other population samples, which will give you an idea of how you are doing, in terms of your asthma-related quality of life. The whole process should take 10-15 minutes, depending on the speed of your connection and how you answer questions. We believe this will be of great interest to anyone with asthma. I invite you to visit our website to see for yourself all that we are trying to accomplish with our project. (http://surveys.pnhs.purdue.edu/index.php?sid=10&token=) If you have any questions or concerns please contact me at murawski@p.p.edu (Replace the p.p in the above address with pharmacy.purdue to reach me)
Respectfully-
-- Matthew M. Murawski,R.Ph.,Ph.D. Associate Professor of Pharmacy Administration Department of Pharmacy Practice Purdue University R.Heine Pharmacy Building Room 502 575 Stadium Mall Drive West Lafayette, IN 47907-2051
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