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GYXE > AsthmaGo to page: « previous | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | next »

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Friday, 3 February 2006
Edgar Cayce's Asthma Treatment Dudley Delany 00:07:18
 
Hi Everyone!

I developed multiple sclerosis in 1991 and, over a two year period,
gradually overcame it using an alternative treatment suggested by Edgar
Cayce, a man many regard as the father of modern holistic medicine.
Cayce also suggested a promising alternative treatment for asthma. For
more information, visit

http://www.webspawn­er.com/users/ecsasth­matx/index.html

All the best,

Dudley Delany, R.N., M.A., D.C.


http://profiles.yah­oo.com/dudley_delany­

comment 13 answers | Add comment
Tuesday, 31 January 2006
New Home HEPA vs ProTech & UV Guest 18:16:32
 My wife and I are custom building a new home in Augusta, GA. I have
seasonal allergies but she's got the whole dust-mite to pollen allergy
list. Our builder recommended we use a whole house filtration system
and we want something highly effective, but not too costly to operate
during the long 90 degree plus summers.

The HVAC contractor has recommended a Protech air cleaning system that
uses a two stage electrostatic precipitation filter followed by a
washable metal mesh pre-filter, then an ionizing filter. We were going
to then follow this with a UV filter.

How would this setup compare to HEPA, or is HEPA too cost prohibitive
to operate due to the static pressure required to push the air through
it? Where would you even get residential HEPA?

Finally, we will have a 2700 sqft main floor with 2 returns, 300 sqft
bonus room and 1100 sqft basement. Should we just filter the main
floor or should we include the basement and/or bonus room, too?

Thanks!

comment 2 answer | Add comment
Sunday, 29 January 2006
So,wheres this "World race for the asthma vaccine" we hear so much about? Guest 05:26:00
 I remember seeing all this talk about asthma vaccines,and now its
suddenly stopped. Anyone have any new-news on these vaccines?

Add comment
COMMON FOOD PRESERVATIVE MIGHT PROVIDE TREATMENT FOR CF Sheldon 05:11:24
 
The following news release is being issued by the University of
Cincinnati and is also being distributed by the U.S. Department of
Energy's Brookhaven National Laboratory. It describes a potential
strategy for treating cystic fibrosis (CF) - an inherited, fatal
disease that affects 30,000 Americans - by using slightly acidified
sodium nitrite, a common food preservative, to kill
antibiotic-resistan­t bacteria that thrive in the mucous-clogged lungs
of CF patients. The study, headed by Daniel Hassett at the University
of Cincinnati, is published in the February 2006 Journal of Clinical
Investigation. Brookhaven Lab chemist Sergei Lymar, one of the key
researchers on the 15 member research team, helped identify the
nitrite-derived species toxic to the bacteria. He also did computer
simulations of the anticipated chemical reactions and helped equip
Hassett's lab to work with nitric oxide. Lymar's work on the study was
funded by the Office of Basic Energy Sciences within the U.S.
Department of Energy's Office of Science.


Brookhaven Lab media contacts:


Karen McNulty Walsh
kmcnulty@bnl.gov
(631) 344-8350


Mona S. Rowe
mrowe@bnl.gov
(631) 344-5056


*******************­********************­*******
University of Cincinnati News Release


EMBARGOED FOR RELEASE
5 p.m. (EST), Thursday, Jan. 26, 2006

CONTACT: David Bracey
david.bracey@uc.edu­
(513) 558-4559

NOTE TO EDITORS: Photos of Dr. Hassett are available by calling (513)
558-4559.

COMMON FOOD PRESERVATIVE MIGHT PROVIDE TREATMENT FOR CYSTIC FIBROSIS

CINCINNATI-Research­ers led by a University of Cincinnati (UC) scientist
say they have discovered what might be the "Achilles' heel" of a
dangerous organism that lives in the lungs of cystic fibrosis
patients-a fatal flaw that leaves the organism vulnerable to
destruction by a common food preservative.

It has been known for some time that the bacterium, Pseudomonas
aeruginosa, grows within the deadly, lung-clogging mucous found in the
airways of cystic fibrosis patients and significantly weakens them.

The new study suggests, however, that a mutation-known as mucA-in the
organism also represents a fatal flaw that could help physicians clear
the characteristic "goop" from the lungs of advanced cystic fibrosis
patients.

The reason for optimism, the researchers say, is that the same genetic
change that turns Pseudomonas aeruginosa into a sticky,
antibiotic-resistan­t killer also leaves it susceptible to destruction
by slightly acidified sodium nitrite, a common chemical that is widely
used in the curing of lunch meat, sausages and bacon.

The finding is reported in the February 2006 edition of the Journal of
Clinical Investigation by a 15-member U.S. and Canadian team headed by
Daniel Hassett, PhD, an associate professor in UC's molecular genetics,
biochemistry and microbiology department. The research was funded by
the U.S. National Institutes of Health, the Cystic Fibrosis Foundation
and the U.S. Department of Energy.

"We believe that we have discovered the Achilles' heel of the
formidable mucoid form of Pseudomonas aeruginosa, which could lead to
improved treatment for cystic fibrosis airway disease," said Dr.
Hassett. "We can essentially say that this organism, which some people
thought could never be beaten, can now be destroyed by nothing more
exotic than a common food preservative."

Cystic fibrosis, which affects about 30,000 people in the United
States, mostly Caucasians of north European origin, is an inherited
disease caused by a defect in a gene called the cystic fibrosis
transmembrane conductance regulator (CFTR). Affecting the airways and
many other vital organs and processes, cystic fibrosis is chronic,
progressive and ultimately fatal, mostly as a result of respiratory
failure.

"The lung-clogging, suffocating mucoid form of Pseudomonas aeruginosa
essentially is a death sentence for cystic fibrosis patients because
these bacteria are inherently antibiotic and white-cell resistant,"
said Dr. Hassett.

Until the 1980s, most deaths from cystic fibrosis occurred in children
and teenagers. Today, thanks to improved treatments, people with cystic
fibrosis live an average of 35 years.
"During the chronic form of cystic fibrosis," Dr. Hassett said, "the
mutated form of the organism, combined with the immune system's
attempts to fight it off, wreaks havoc in the lungs.

"When Pseudomonas aeruginosa invades the mucous that's built up in the
airways," said Dr. Hassett, "it forms a resistant 'biofilm,' like that
which occurs on teeth or a toilet bowl, and divides rapidly.

"White cells from our immune system try to get in there to fight off
the invaders," he added, "but they can't reach the bacteria to kill
them because they're enmeshed in that thick mucous, essentially a human
form of 'quicksand.' So in trying to defend the body against the
Pseudomonas aeruginosa, the white blood cells end up dumping toxic,
damaging material onto the airway surfaces, which leads to lung
destruction.

"This biofilm lines the whole area, getting thicker and thicker and
developing into a dense layer that deprives surface tissue of oxygen,
ultimately killing it. So it's not only the bacteria that contribute to
the disease, it's also our own immune system."

The good news is that Dr. Hassett and his colleagues found that about
87 percent of the mucoid Pseudomonas organisms they studied have a
"fatal flaw" in the very gene (mucA) that makes it mucoid as well as
antibiotic and immune-system resistant-they are easily destroyed by
slightly acidified (pH 6.5) sodium nitrite.

Part of the problem with early and chronic cystic fibrosis, Dr. Hassett
explained, is that patients with these conditions make very little
nitric oxide, a derivative of acidified sodium nitrite.

"Mucoid Pseudomonas aeruginosa bacteria should have enzymes that are
able to dispose of both nitrite and nitric oxide," Dr. Hassett said,
"but for whatever reason, this particular bug doesn't make them, or has
very low levels of them.

"That's the fatal flaw in mucoid Pseudomonas aeruginosa."

Dr. Hassett and his colleagues had worked on the hypothesis that the
mucoid bacteria-because they flourish in patients who are essentially
drowning in their own airway mucous-would grow better using nitrate or
nitrite as an alternative to the missing oxygen. But when they tested
nonmucoid and mucoid forms, the nonmucoids grew with both nitrate and
nitrite without oxygen, while the mucoid organism grew only with
nitrate, yet died with nitrite.

The team took about 60 mucoid bacteria from six different clinics in
the United States and Canada and found that of all the strains that
were mucoid, the ones that had mucA mutations were all sensitive to
nitrite, and those that are notoriously antibiotic resistant were even
more sensitive.

"Sodium nitrite kills the mucoids, and if nonmucoids or other bacteria
are present in the airways, it inhibits their growth too," said Dr.
Hassett.

"When we add slightly acidified sodium nitrite to a suspension
containing mucoid bacteria, it's converted to the gas nitric oxide,"
said Dr. Hassett. "The mucoid bacteria can't dispose of the nitrite
metabolically, and also have difficulty handling the gas, so they die.

"Here was something we hypothesized that would allow mucoid bacteria to
grow much better than nonmucoid bacteria, but instead it killed them,"
said Dr. Hassett. "In plain English, these bacteria had a defect that
we didn't anticipate. I've never been so happy in my life to be wrong!"

Sodium nitrite, Dr. Hassett said, has potential as "a time-release"
capsule for cystic fibrosis patients. Because the nitrite is degraded
very slowly, and mucoid bacteria can't get rid of it, it should
specifically kill mucoid organisms that have the mucA mutation-which
most do.
Dr. Hassett said he envisions sodium nitrite could be used in aerosol
form to treat mucoid Pseudomonas aeruginosa in cystic fibrosis lung
disease.

"This wouldn't need to be a long-term treatment," he said. "Once a
patient acquires mucoids, which commonly occur, the physician would
simply use sodium nitrite and monitor how many mucoid bacteria are
still in airway sputum. Once the mucoid organisms are killed, and the
patient starts showing signs of improvement, treatment would continue
with conventional antibiotics."

But bringing this treatment to the bedside won't be easy, Dr. Hassett
conceded.
"Right now, we don't see the Food and Drug Administration approving
blowing sodium nitrite into people's airways, because it may
potentially have some toxic side effects.
"However, nitrites are used clinically, to counteract cyanide
poisoning, warts and athlete's foot, for example. And in neonatal
pulmonary hypertension, physicians may be using nitrite doses nearly 60
times higher than we use to kill the organism in mouse and human airway
cells."

Key researchers on the 15-member research team with Dr. Hassett were
San Sun Yoon, formerly with the University of Cincinnati and now at
Harvard Medical School, Sergei Lymar, Brookhaven National Laboratory,
and Richard Boucher, University of North Carolina.

--

Media & Communications Office (631) 344-2345 phone
Community, Education, Government (631) 344-8350 phone
& Public Affairs Directorate (631) 344-3368 fax
Brookhaven National Laboratory pubaf@bnl.gov
Upton NY 11973 www.bnl.gov
---

Sheldon

comment 3 answer | Add comment
Friday, 27 January 2006
Dust Mites RyanCSpgs 11:51:44
 I just started immunotherapy here in Colorado to help with seasonal
asthma and allergies. My allergist says that although I am allergic to
both types of dust mites (My skin test showed 20-22mm dust mites, 11mm
for histamine baseline), he recommended that I skip the dust mites
extract as part of the serum. The reason is that dust mites don't
thrive in low humidity climates like we have here in Colorado. Does
anyone have experience with immunotherapy and does this sound like good
advice?
Thanks,
Ryan

comment 2 answer | Add comment
health search engine Alison Chaiken 04:39:18
 
I hear from reputable sources that this health-info site is worth
checking out:

http://www.healthli­ne.com/

For example, from the "asthma channel" I learn that "FDA Decision
Could Mean Fewer OTC Options for Asthma Patients:"

http://www.wishtv.c­om/Global/story.asp?­S=4411100

which contains news I didn't know about Primatene possibly being
pulled.

Non-disclaimer: I have nothing to do with this website.

--
Alison Chaiken "From:" address above is valid.
(650) 236-2231 [daytime]http://www.wsrcc.co­m/alison/
Waging a war is simple, but running a country is very difficult.
-- Pham Van Dong, first prime minister of unified Vietnam, 1976

comment 2 answer | Add comment
Thursday, 26 January 2006
Wheresgeorge.com helps scientists NorthShoreCEO 18:55:07
 http://www.usatoday.­com/tech/science/dis­coveries/2006-01-25-­website-prediction_x­.htm



Add comment
Wednesday, 25 January 2006
Can indoor ficus tree cause asthma? Fjv 15:44:38
 I just learned from a homeopathic doctor that ornamental ficus trees (Ficus
Benjamina) can cause asthma. Is it true and is there an allergy test for it?
Any insight would be appreciated.


comment 1 answer | Add comment
Mantak Chia Richard Friedel 00:19:54
 Mantak Chia is a teacher of taoist (daoist) breathing techniques and a
prolific author. Two of his exercises in the book "Tan Tien Chi Kung"
are available at
http://www.lrz-muen­chen.de/~s3e0101/web­server/webdata/Manta­kChia.doc

Whether people agree with me or not on the effectiveness of "perineum
power" and "sucking up the upper abdomen" as a method for treating
asthma, he does seem to cast quite a different light on breathing
generally.

His book does however contain a strict warning that the techniques
should only be learned from a qualified teacher and that learning from
the book alone would be dangerous. Regards, Richard Friedel

Add comment
Tuesday, 24 January 2006
FAO parents of child with Asthma Kcooke 17:40:29
 I need your help. Im conducting a short questionnaire for parents of
children with asthma, that has caused them to visit hospitals. The
purpose of the questionnaire is to find out how the children have
experienced their visits in hospitals.

If you are willing to give up your time to help create a better
understanding of childrens expereinces of hospitals please email me at
kcooke1@ucc.ac.uk or at cherrykisss@hotmail­.com and i shall email you a
copy of the questionnaire.

Many Thanks to you.

Add comment
ragweed drug Alison Chaiken 05:12:51
 
http://www.mercuryn­ews.com/mld/mercuryn­ews/business/1366941­3.htm

Shares of Dynavax Technologies soared Thursday, after the
Berkeley pharmaceutical company said its ragweed allergy
drug, Tolamba, met primary efficacy and safety endpoints in
a clinical trial. Dynavax stock rose $1.48, or 34 percent,
to close at $5.83 Thursday on the Nasdaq Stock Market.

Just what we need, a different drug for each allergy. Is there any
possible justification for a special drug for ragweed allergy?

--
Alison Chaiken "From:" address above is valid.
(650) 236-2231 [daytime]http://www.wsrcc.co­m/alison/
Waging a war is simple, but running a country is very difficult.
-- Pham Van Dong, first prime minister of unified Vietnam, 1976

comment 4 answer | Add comment
Monday, 23 January 2006
Saiboku-to (TJ-96), a "Japanese Government approved" herbal complex Richard Friedel 19:17:00
 See
http://www.famousch­inese.com/viewmedlin­e?id=12117049&cdate=­07/15/2002.
Regards, Richard Friedel

Add comment
triggered by eating Pete 19:10:54
 Has anyone ever heard of this? Asthma attacks triggered by simply eating. I
don't mean allergy or intolerance to any particular food, or a delayed
reaction, but, simply eating a typical supper-sized meal. Just eating, then
while eating or immediately after, tight feeling starts quickly followed by
difficulty breathing. A couple of puffs of ventolin relieves it.

Thanks
Pete


comment 4 answer | Add comment
Sunday, 22 January 2006
It's about time... Aroberts 19:35:00
 
The FDA is finally starting to crack down on pharma advertising. We'll
see how aggressively they do this. It certainly took them long enough.


http://www.medscape­.com/viewarticle/513­085?src=mp

comment 10 answers | Add comment
Saturday, 21 January 2006
asthmatic seeking air cleaner/purifier recommendations J W 02:31:24
 Thank you in advance for your time and recommendations. I have bad
allergies and COPD/asthma and am trying to determine which is the most
effective make and model of air cleaner or purifier. There are many
brands at many different price levels. Some with filters that need
replacing and some that do not. It is very confusing. I have recently
purchased one of the sharper image ionic breeze models with the gadget
that converts ozone to oxygen as it requires no expensive filter to
replace. But after receiving it I noticed in the instruction manual it
states that people with asthma, heart problems or any lung problems
should consult a doctor before using this product, plus it emits a
rather foul odor when running

These facts were not stated on the website and I find it a bit
disturbing. I bought the thing to clean the air and help my lung
condition and now find it may not be advisable for those with lung
conditions. I'll probably return it.

What I'm asking of the group since this ionic breeze thing seems to not
be advisable is what would be the best type and model of air cleaner for
me to get? I need something that will clean a fairly large area as the
main living area of our house has large rooms and also something that
isn't super expensive to buy and maintain.




comment 3 answer | Add comment
Thursday, 19 January 2006
Merlin, The Gambler... Aroberts 18:18:10
 
The Gambler (sorry Kenny Rogers)

On any given evenin', comes a goof from out of nowhere,
offering to wager--to prove he's not a creep.
He takes turns a' braggin' about how he cures those diseases
with long-winded diatribes that can put you fast asleep.

He says "Son, I've made a life out of spinnin' tales and lyin'
to inflate my sense of self-worth and to pat my own back.
I write long and senseless postings, just to see my thoughts on usenet,
without a grain of truth, and a disregard for fact."

Chorus:

You've got to know when to tell 'em, know how to sell 'em
that you're a shaman, a doctor, big cheese.
You never admit that you're looney, that it's all a big fable,
that in your case it's lying that's the uncurable disease.

Now all BS artists know that the secret to survivin'
is to get mad and call folks names, just to hide your own shame.
But everybody knows that Merlin has just been jivin'
about everything he's written, and that includes his name. (Sing it
Larry!)

So when he finds that no one's buyin', we hope he'll quit his posting
as he has promised to, so many times before.
Or that somewhere in the ward, they'll lock up the computer,
and deny him access to his fantasies galore.

Chorus:

You've got to know when to tell 'em, know how to sell 'em
that you're a shaman, a doctor, big cheese.
You never admit that you're looney, that it's all a big fable,
that in your case it's lying that's the uncurable disease.

comment 1 answer | Add comment
Tuesday, 17 January 2006
Advair Warning Dave 03:33:23
 Oct. 7, 2005


GlaxoSmithKline Misled FDA, Doctors and Patients with Faulty Asthma
Drug
Study, Public Citizen Writes in Lancet Medical Journal


Drug Maker Included Data From Six Months After Trial Ended, Skewing
Results


WASHINGTON, D.C. - GlaxoSmithKline presented misleading results to the
Food and Drug Administration (FDA) from a study of the popular asthma
drug salmeterol (Serevent, known as Advair when combined with the
steroid fluticasone), Public Citizen writes in a letter in this week's
issue of The Lancet.


In 1996, the Salmeterol Multicenter Asthma Research Trial was initiated



to study tens of thousands of asthma patients who received either
salmeterol or a placebo. The study lasted 28 weeks and showed an
increased risk of asthma-related death for those taking salmeterol. The



results have never been published, although GlaxoSmithKline presented
the interim results to the FDA in July 2003, when the drug came up for
review before the FDA's Pulmonary-Allergy Drugs Advisory Committee. The



company submitted final study data to the FDA on August 29, 2003.


However, that data included adverse events that were reported six
months
after the trial ended and were not to be included, according to the
original study protocol. The inclusion of the post-study data reduced
the apparent dangers of salmeterol with respect to four critical study
outcomes, including asthma-related death.


GlaxoSmithKline did not clearly inform the FDA that the final study
included data from six months after the trial had concluded until the
FDA inquired about the results in April 2004. The FDA had presumed the
data were only from the 28-week trial itself, since that was the
"period
of interest," according to the FDA.


Since learning of the suspicious reporting of the study results, the
FDA's Pulmonary-Allergy Drugs Advisory Committee on July 13, 2005,
recommended strengthening the warning on the labels for both Servent
and
Advair, but the agency has yet to make a final decision. Public Citizen



learned of the misleading data presentation from materials provided to
the advisory committee.


"The behavior of GlaxoSmithKline in submitting these faulty data is
deplorable," said Dr. Peter Lurie, deputy director of Public Citizen's
Health Research Group and co-author of the letter. "Absent greater
transparency at the FDA, we will never know how often this kind of
self-serving data analysis occurs."


Public Citizen listed Serevent as a "Do Not Use" drug in its Worst
Pills, Best Pills newsletter (www.worstpills.org­) in March 2003 because



of the interim study results.


Salmeterol was dispensed more than 2.1 million times in U.S. pharmacies



in 2004. The combination product, Advair, was dispensed more than 16.1
million times in U.S. pharmacies that year.

comment 13 answers | Add comment
Monday, 16 January 2006
Report: Fish oil can prevent airway constriction in asthma Keith Winkler 06:19:54
 Fish oil can prevent airway constriction in asthma



Reuters Health

Monday, January 9, 2006

By Anthony J. Brown, MD

NEW YORK (Reuters Health) - Adding fish oil supplements to the diet can
prevent the constriction of the airways brought on by exercise in
asthmatics, a very common problem in this patient group, new research shows.

In an earlier study, Dr. Timothy D. Mickleborough, from Indiana University
in Bloomington, and colleagues had shown that fish oil supplements can
improve lung function in elite athletes with bronchoconstriction­ (EIB), but
their use in asthmatics with the condition had not been well studied.

"The current findings suggest that fish oil supplements may be of value to
asthmatics with EIB," Mickleborough told Reuters Health. "Our results
support previous reports suggesting that the benefits are mediated through
the antiinflammatory effects of fish oil."

The researchers assessed pre- and postexercise lung function and sputum
inflammatory markers in 16 asthma patients with EIB who were randomly
assigned to a normal diet supplemented with fish oil capsules or with
placebo for three weeks. After a two-week interval, in which no supplements
or placebos were given, the patients switched to the other regimen.

With the normal diet alone as well as the placebo-supplemente­d diet, the
participants developed EIB. By contrast, with fish oil supplementation, the
decrease in lung function that occurred with exercise was smaller and did
not reach the threshold needed for an EIB diagnosis. In addition, with the
supplements, the subjects were able to cut back on bronchodilator usage.

Compared with the other diets, the fish oil-supplemented diet was associated
with a significant drop in a number of markers of inflammation in the
sputum, which was noted both before and after exercise.

Mickleborough said the study subjects received 20 capsules of fish oil per
day, in keeping with the dose his team had used in their earlier study, and
suspects this may make patients less compliant. However, he hopes to conduct
a dose-finding study in the future, which could result in the use of a much
smaller dose.

SOURCE: Chest January 2006.


Add comment
Sunday, 15 January 2006
Re: Second-Hand cigarette smoke? Bruce Watson 19:41:46
 In article <at1bs1l31k0nkrlv14­stb8cq65de72ofc4@lol­.com>,
Theodore Baldwin Boothe III <DNC_TN@YAHOO.COM> wrote:
I was wondering if ramona kicks the bucket if it would be because of>2nd hand smoke/????
I mean, she has inhaled smoke from art's 18 pack a day habit for years>and it has had to have an effect on her lungs?

Certainly, with her asthma, he smoked outside.
comment 13 answers | Add comment

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