Friday, 3 February 2006
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| Edgar Cayce's Asthma Treatment Dudley Delany 00:07:18 |
| | Hi Everyone!
I developed multiple sclerosis in 1991 and, over a two year period, gradually overcame it using an alternative treatment suggested by Edgar Cayce, a man many regard as the father of modern holistic medicine. Cayce also suggested a promising alternative treatment for asthma. For more information, visit
http://www.webspawner.com/users/ecsasthmatx/index.html
All the best,
Dudley Delany, R.N., M.A., D.C.
http://profiles.yahoo.com/dudley_delany
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Tuesday, 31 January 2006
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| New Home HEPA vs ProTech & UV Guest 18:16:32 |
| | My wife and I are custom building a new home in Augusta, GA. I have seasonal allergies but she's got the whole dust-mite to pollen allergy list. Our builder recommended we use a whole house filtration system and we want something highly effective, but not too costly to operate during the long 90 degree plus summers.
The HVAC contractor has recommended a Protech air cleaning system that uses a two stage electrostatic precipitation filter followed by a washable metal mesh pre-filter, then an ionizing filter. We were going to then follow this with a UV filter.
How would this setup compare to HEPA, or is HEPA too cost prohibitive to operate due to the static pressure required to push the air through it? Where would you even get residential HEPA?
Finally, we will have a 2700 sqft main floor with 2 returns, 300 sqft bonus room and 1100 sqft basement. Should we just filter the main floor or should we include the basement and/or bonus room, too?
Thanks!
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Sunday, 29 January 2006
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| So,wheres this "World race for the asthma vaccine" we hear so much about? Guest 05:26:00 |
| | I remember seeing all this talk about asthma vaccines,and now its suddenly stopped. Anyone have any new-news on these vaccines?
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| COMMON FOOD PRESERVATIVE MIGHT PROVIDE TREATMENT FOR CF Sheldon 05:11:24 |
| | The following news release is being issued by the University of Cincinnati and is also being distributed by the U.S. Department of Energy's Brookhaven National Laboratory. It describes a potential strategy for treating cystic fibrosis (CF) - an inherited, fatal disease that affects 30,000 Americans - by using slightly acidified sodium nitrite, a common food preservative, to kill antibiotic-resistant bacteria that thrive in the mucous-clogged lungs of CF patients. The study, headed by Daniel Hassett at the University of Cincinnati, is published in the February 2006 Journal of Clinical Investigation. Brookhaven Lab chemist Sergei Lymar, one of the key researchers on the 15 member research team, helped identify the nitrite-derived species toxic to the bacteria. He also did computer simulations of the anticipated chemical reactions and helped equip Hassett's lab to work with nitric oxide. Lymar's work on the study was funded by the Office of Basic Energy Sciences within the U.S. Department of Energy's Office of Science.
Brookhaven Lab media contacts:
Karen McNulty Walsh kmcnulty@bnl.gov (631) 344-8350
Mona S. Rowe mrowe@bnl.gov (631) 344-5056
********************************************** University of Cincinnati News Release
EMBARGOED FOR RELEASE 5 p.m. (EST), Thursday, Jan. 26, 2006
CONTACT: David Bracey david.bracey@uc.edu (513) 558-4559
NOTE TO EDITORS: Photos of Dr. Hassett are available by calling (513) 558-4559.
COMMON FOOD PRESERVATIVE MIGHT PROVIDE TREATMENT FOR CYSTIC FIBROSIS
CINCINNATI-Researchers led by a University of Cincinnati (UC) scientist say they have discovered what might be the "Achilles' heel" of a dangerous organism that lives in the lungs of cystic fibrosis patients-a fatal flaw that leaves the organism vulnerable to destruction by a common food preservative.
It has been known for some time that the bacterium, Pseudomonas aeruginosa, grows within the deadly, lung-clogging mucous found in the airways of cystic fibrosis patients and significantly weakens them.
The new study suggests, however, that a mutation-known as mucA-in the organism also represents a fatal flaw that could help physicians clear the characteristic "goop" from the lungs of advanced cystic fibrosis patients.
The reason for optimism, the researchers say, is that the same genetic change that turns Pseudomonas aeruginosa into a sticky, antibiotic-resistant killer also leaves it susceptible to destruction by slightly acidified sodium nitrite, a common chemical that is widely used in the curing of lunch meat, sausages and bacon.
The finding is reported in the February 2006 edition of the Journal of Clinical Investigation by a 15-member U.S. and Canadian team headed by Daniel Hassett, PhD, an associate professor in UC's molecular genetics, biochemistry and microbiology department. The research was funded by the U.S. National Institutes of Health, the Cystic Fibrosis Foundation and the U.S. Department of Energy.
"We believe that we have discovered the Achilles' heel of the formidable mucoid form of Pseudomonas aeruginosa, which could lead to improved treatment for cystic fibrosis airway disease," said Dr. Hassett. "We can essentially say that this organism, which some people thought could never be beaten, can now be destroyed by nothing more exotic than a common food preservative."
Cystic fibrosis, which affects about 30,000 people in the United States, mostly Caucasians of north European origin, is an inherited disease caused by a defect in a gene called the cystic fibrosis transmembrane conductance regulator (CFTR). Affecting the airways and many other vital organs and processes, cystic fibrosis is chronic, progressive and ultimately fatal, mostly as a result of respiratory failure.
"The lung-clogging, suffocating mucoid form of Pseudomonas aeruginosa essentially is a death sentence for cystic fibrosis patients because these bacteria are inherently antibiotic and white-cell resistant," said Dr. Hassett.
Until the 1980s, most deaths from cystic fibrosis occurred in children and teenagers. Today, thanks to improved treatments, people with cystic fibrosis live an average of 35 years. "During the chronic form of cystic fibrosis," Dr. Hassett said, "the mutated form of the organism, combined with the immune system's attempts to fight it off, wreaks havoc in the lungs.
"When Pseudomonas aeruginosa invades the mucous that's built up in the airways," said Dr. Hassett, "it forms a resistant 'biofilm,' like that which occurs on teeth or a toilet bowl, and divides rapidly.
"White cells from our immune system try to get in there to fight off the invaders," he added, "but they can't reach the bacteria to kill them because they're enmeshed in that thick mucous, essentially a human form of 'quicksand.' So in trying to defend the body against the Pseudomonas aeruginosa, the white blood cells end up dumping toxic, damaging material onto the airway surfaces, which leads to lung destruction.
"This biofilm lines the whole area, getting thicker and thicker and developing into a dense layer that deprives surface tissue of oxygen, ultimately killing it. So it's not only the bacteria that contribute to the disease, it's also our own immune system."
The good news is that Dr. Hassett and his colleagues found that about 87 percent of the mucoid Pseudomonas organisms they studied have a "fatal flaw" in the very gene (mucA) that makes it mucoid as well as antibiotic and immune-system resistant-they are easily destroyed by slightly acidified (pH 6.5) sodium nitrite.
Part of the problem with early and chronic cystic fibrosis, Dr. Hassett explained, is that patients with these conditions make very little nitric oxide, a derivative of acidified sodium nitrite.
"Mucoid Pseudomonas aeruginosa bacteria should have enzymes that are able to dispose of both nitrite and nitric oxide," Dr. Hassett said, "but for whatever reason, this particular bug doesn't make them, or has very low levels of them.
"That's the fatal flaw in mucoid Pseudomonas aeruginosa."
Dr. Hassett and his colleagues had worked on the hypothesis that the mucoid bacteria-because they flourish in patients who are essentially drowning in their own airway mucous-would grow better using nitrate or nitrite as an alternative to the missing oxygen. But when they tested nonmucoid and mucoid forms, the nonmucoids grew with both nitrate and nitrite without oxygen, while the mucoid organism grew only with nitrate, yet died with nitrite.
The team took about 60 mucoid bacteria from six different clinics in the United States and Canada and found that of all the strains that were mucoid, the ones that had mucA mutations were all sensitive to nitrite, and those that are notoriously antibiotic resistant were even more sensitive.
"Sodium nitrite kills the mucoids, and if nonmucoids or other bacteria are present in the airways, it inhibits their growth too," said Dr. Hassett.
"When we add slightly acidified sodium nitrite to a suspension containing mucoid bacteria, it's converted to the gas nitric oxide," said Dr. Hassett. "The mucoid bacteria can't dispose of the nitrite metabolically, and also have difficulty handling the gas, so they die.
"Here was something we hypothesized that would allow mucoid bacteria to grow much better than nonmucoid bacteria, but instead it killed them," said Dr. Hassett. "In plain English, these bacteria had a defect that we didn't anticipate. I've never been so happy in my life to be wrong!"
Sodium nitrite, Dr. Hassett said, has potential as "a time-release" capsule for cystic fibrosis patients. Because the nitrite is degraded very slowly, and mucoid bacteria can't get rid of it, it should specifically kill mucoid organisms that have the mucA mutation-which most do. Dr. Hassett said he envisions sodium nitrite could be used in aerosol form to treat mucoid Pseudomonas aeruginosa in cystic fibrosis lung disease.
"This wouldn't need to be a long-term treatment," he said. "Once a patient acquires mucoids, which commonly occur, the physician would simply use sodium nitrite and monitor how many mucoid bacteria are still in airway sputum. Once the mucoid organisms are killed, and the patient starts showing signs of improvement, treatment would continue with conventional antibiotics."
But bringing this treatment to the bedside won't be easy, Dr. Hassett conceded. "Right now, we don't see the Food and Drug Administration approving blowing sodium nitrite into people's airways, because it may potentially have some toxic side effects. "However, nitrites are used clinically, to counteract cyanide poisoning, warts and athlete's foot, for example. And in neonatal pulmonary hypertension, physicians may be using nitrite doses nearly 60 times higher than we use to kill the organism in mouse and human airway cells."
Key researchers on the 15-member research team with Dr. Hassett were San Sun Yoon, formerly with the University of Cincinnati and now at Harvard Medical School, Sergei Lymar, Brookhaven National Laboratory, and Richard Boucher, University of North Carolina.
--
Media & Communications Office (631) 344-2345 phone Community, Education, Government (631) 344-8350 phone & Public Affairs Directorate (631) 344-3368 fax Brookhaven National Laboratory pubaf@bnl.gov Upton NY 11973 www.bnl.gov ---
Sheldon
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Friday, 27 January 2006
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| Dust Mites RyanCSpgs 11:51:44 |
| | I just started immunotherapy here in Colorado to help with seasonal asthma and allergies. My allergist says that although I am allergic to both types of dust mites (My skin test showed 20-22mm dust mites, 11mm for histamine baseline), he recommended that I skip the dust mites extract as part of the serum. The reason is that dust mites don't thrive in low humidity climates like we have here in Colorado. Does anyone have experience with immunotherapy and does this sound like good advice? Thanks, Ryan
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| health search engine Alison Chaiken 04:39:18 |
| | I hear from reputable sources that this health-info site is worth checking out:
http://www.healthline.com/
For example, from the "asthma channel" I learn that "FDA Decision Could Mean Fewer OTC Options for Asthma Patients:"
http://www.wishtv.com/Global/story.asp?S=4411100
which contains news I didn't know about Primatene possibly being pulled.
Non-disclaimer: I have nothing to do with this website.
-- Alison Chaiken "From:" address above is valid. (650) 236-2231 [daytime]http://www.wsrcc.com/alison/ Waging a war is simple, but running a country is very difficult. -- Pham Van Dong, first prime minister of unified Vietnam, 1976
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Thursday, 26 January 2006
Wednesday, 25 January 2006
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| Can indoor ficus tree cause asthma? Fjv 15:44:38 |
| | I just learned from a homeopathic doctor that ornamental ficus trees (Ficus Benjamina) can cause asthma. Is it true and is there an allergy test for it? Any insight would be appreciated.
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| Mantak Chia Richard Friedel 00:19:54 |
| | Mantak Chia is a teacher of taoist (daoist) breathing techniques and a prolific author. Two of his exercises in the book "Tan Tien Chi Kung" are available at http://www.lrz-muenchen.de/~s3e0101/webserver/webdata/MantakChia.doc
Whether people agree with me or not on the effectiveness of "perineum power" and "sucking up the upper abdomen" as a method for treating asthma, he does seem to cast quite a different light on breathing generally.
His book does however contain a strict warning that the techniques should only be learned from a qualified teacher and that learning from the book alone would be dangerous. Regards, Richard Friedel
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Tuesday, 24 January 2006
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| FAO parents of child with Asthma Kcooke 17:40:29 |
| | I need your help. Im conducting a short questionnaire for parents of children with asthma, that has caused them to visit hospitals. The purpose of the questionnaire is to find out how the children have experienced their visits in hospitals.
If you are willing to give up your time to help create a better understanding of childrens expereinces of hospitals please email me at kcooke1@ucc.ac.uk or at cherrykisss@hotmail.com and i shall email you a copy of the questionnaire.
Many Thanks to you.
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| ragweed drug Alison Chaiken 05:12:51 |
| | http://www.mercurynews.com/mld/mercurynews/business/13669413.htm
Shares of Dynavax Technologies soared Thursday, after the Berkeley pharmaceutical company said its ragweed allergy drug, Tolamba, met primary efficacy and safety endpoints in a clinical trial. Dynavax stock rose $1.48, or 34 percent, to close at $5.83 Thursday on the Nasdaq Stock Market.
Just what we need, a different drug for each allergy. Is there any possible justification for a special drug for ragweed allergy?
-- Alison Chaiken "From:" address above is valid. (650) 236-2231 [daytime]http://www.wsrcc.com/alison/ Waging a war is simple, but running a country is very difficult. -- Pham Van Dong, first prime minister of unified Vietnam, 1976
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Monday, 23 January 2006
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| triggered by eating Pete 19:10:54 |
| | Has anyone ever heard of this? Asthma attacks triggered by simply eating. I don't mean allergy or intolerance to any particular food, or a delayed reaction, but, simply eating a typical supper-sized meal. Just eating, then while eating or immediately after, tight feeling starts quickly followed by difficulty breathing. A couple of puffs of ventolin relieves it.
Thanks Pete
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Sunday, 22 January 2006
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| It's about time... Aroberts 19:35:00 |
| | The FDA is finally starting to crack down on pharma advertising. We'll see how aggressively they do this. It certainly took them long enough.
http://www.medscape.com/viewarticle/513085?src=mp
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Saturday, 21 January 2006
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| asthmatic seeking air cleaner/purifier recommendations J W 02:31:24 |
| | Thank you in advance for your time and recommendations. I have bad allergies and COPD/asthma and am trying to determine which is the most effective make and model of air cleaner or purifier. There are many brands at many different price levels. Some with filters that need replacing and some that do not. It is very confusing. I have recently purchased one of the sharper image ionic breeze models with the gadget that converts ozone to oxygen as it requires no expensive filter to replace. But after receiving it I noticed in the instruction manual it states that people with asthma, heart problems or any lung problems should consult a doctor before using this product, plus it emits a rather foul odor when running
These facts were not stated on the website and I find it a bit disturbing. I bought the thing to clean the air and help my lung condition and now find it may not be advisable for those with lung conditions. I'll probably return it.
What I'm asking of the group since this ionic breeze thing seems to not be advisable is what would be the best type and model of air cleaner for me to get? I need something that will clean a fairly large area as the main living area of our house has large rooms and also something that isn't super expensive to buy and maintain.
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Thursday, 19 January 2006
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| Merlin, The Gambler... Aroberts 18:18:10 |
| | The Gambler (sorry Kenny Rogers)
On any given evenin', comes a goof from out of nowhere, offering to wager--to prove he's not a creep. He takes turns a' braggin' about how he cures those diseases with long-winded diatribes that can put you fast asleep.
He says "Son, I've made a life out of spinnin' tales and lyin' to inflate my sense of self-worth and to pat my own back. I write long and senseless postings, just to see my thoughts on usenet, without a grain of truth, and a disregard for fact."
Chorus:
You've got to know when to tell 'em, know how to sell 'em that you're a shaman, a doctor, big cheese. You never admit that you're looney, that it's all a big fable, that in your case it's lying that's the uncurable disease.
Now all BS artists know that the secret to survivin' is to get mad and call folks names, just to hide your own shame. But everybody knows that Merlin has just been jivin' about everything he's written, and that includes his name. (Sing it Larry!)
So when he finds that no one's buyin', we hope he'll quit his posting as he has promised to, so many times before. Or that somewhere in the ward, they'll lock up the computer, and deny him access to his fantasies galore.
Chorus:
You've got to know when to tell 'em, know how to sell 'em that you're a shaman, a doctor, big cheese. You never admit that you're looney, that it's all a big fable, that in your case it's lying that's the uncurable disease.
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Tuesday, 17 January 2006
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| Advair Warning Dave 03:33:23 |
| | Oct. 7, 2005
GlaxoSmithKline Misled FDA, Doctors and Patients with Faulty Asthma Drug Study, Public Citizen Writes in Lancet Medical Journal
Drug Maker Included Data From Six Months After Trial Ended, Skewing Results
WASHINGTON, D.C. - GlaxoSmithKline presented misleading results to the Food and Drug Administration (FDA) from a study of the popular asthma drug salmeterol (Serevent, known as Advair when combined with the steroid fluticasone), Public Citizen writes in a letter in this week's issue of The Lancet.
In 1996, the Salmeterol Multicenter Asthma Research Trial was initiated
to study tens of thousands of asthma patients who received either salmeterol or a placebo. The study lasted 28 weeks and showed an increased risk of asthma-related death for those taking salmeterol. The
results have never been published, although GlaxoSmithKline presented the interim results to the FDA in July 2003, when the drug came up for review before the FDA's Pulmonary-Allergy Drugs Advisory Committee. The
company submitted final study data to the FDA on August 29, 2003.
However, that data included adverse events that were reported six months after the trial ended and were not to be included, according to the original study protocol. The inclusion of the post-study data reduced the apparent dangers of salmeterol with respect to four critical study outcomes, including asthma-related death.
GlaxoSmithKline did not clearly inform the FDA that the final study included data from six months after the trial had concluded until the FDA inquired about the results in April 2004. The FDA had presumed the data were only from the 28-week trial itself, since that was the "period of interest," according to the FDA.
Since learning of the suspicious reporting of the study results, the FDA's Pulmonary-Allergy Drugs Advisory Committee on July 13, 2005, recommended strengthening the warning on the labels for both Servent and Advair, but the agency has yet to make a final decision. Public Citizen
learned of the misleading data presentation from materials provided to the advisory committee.
"The behavior of GlaxoSmithKline in submitting these faulty data is deplorable," said Dr. Peter Lurie, deputy director of Public Citizen's Health Research Group and co-author of the letter. "Absent greater transparency at the FDA, we will never know how often this kind of self-serving data analysis occurs."
Public Citizen listed Serevent as a "Do Not Use" drug in its Worst Pills, Best Pills newsletter (www.worstpills.org) in March 2003 because
of the interim study results.
Salmeterol was dispensed more than 2.1 million times in U.S. pharmacies
in 2004. The combination product, Advair, was dispensed more than 16.1 million times in U.S. pharmacies that year.
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Monday, 16 January 2006
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| Report: Fish oil can prevent airway constriction in asthma Keith Winkler 06:19:54 |
| | Fish oil can prevent airway constriction in asthma
Reuters Health
Monday, January 9, 2006
By Anthony J. Brown, MD
NEW YORK (Reuters Health) - Adding fish oil supplements to the diet can prevent the constriction of the airways brought on by exercise in asthmatics, a very common problem in this patient group, new research shows.
In an earlier study, Dr. Timothy D. Mickleborough, from Indiana University in Bloomington, and colleagues had shown that fish oil supplements can improve lung function in elite athletes with bronchoconstriction (EIB), but their use in asthmatics with the condition had not been well studied.
"The current findings suggest that fish oil supplements may be of value to asthmatics with EIB," Mickleborough told Reuters Health. "Our results support previous reports suggesting that the benefits are mediated through the antiinflammatory effects of fish oil."
The researchers assessed pre- and postexercise lung function and sputum inflammatory markers in 16 asthma patients with EIB who were randomly assigned to a normal diet supplemented with fish oil capsules or with placebo for three weeks. After a two-week interval, in which no supplements or placebos were given, the patients switched to the other regimen.
With the normal diet alone as well as the placebo-supplemented diet, the participants developed EIB. By contrast, with fish oil supplementation, the decrease in lung function that occurred with exercise was smaller and did not reach the threshold needed for an EIB diagnosis. In addition, with the supplements, the subjects were able to cut back on bronchodilator usage.
Compared with the other diets, the fish oil-supplemented diet was associated with a significant drop in a number of markers of inflammation in the sputum, which was noted both before and after exercise.
Mickleborough said the study subjects received 20 capsules of fish oil per day, in keeping with the dose his team had used in their earlier study, and suspects this may make patients less compliant. However, he hopes to conduct a dose-finding study in the future, which could result in the use of a much smaller dose.
SOURCE: Chest January 2006.
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Sunday, 15 January 2006
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| Re: Second-Hand cigarette smoke? Bruce Watson 19:41:46 |
| | In article <at1bs1l31k0nkrlv14stb8cq65de72ofc4@lol.com>, Theodore Baldwin Boothe III <DNC_TN@YAHOO.COM> wrote:
I was wondering if ramona kicks the bucket if it would be because of>2nd hand smoke/???? I mean, she has inhaled smoke from art's 18 pack a day habit for years>and it has had to have an effect on her lungs? Certainly, with her asthma, he smoked outside.
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